KMID : 0032220100220040468
|
|
Annals of Dermatology 2010 Volume.22 No. 4 p.468 ~ p.471
|
|
Penicillamine-induced Elastosis Perforans Serpiginosa and Cutis Laxa in a Patient with Wilson¡¯s Disease
|
|
Na Se-Young
Choi Mi-Ra Kim Min-Ji Lee Jong-Hee Cho So-Yun
|
|
Abstract
|
|
|
Elastosis perforans serpiginosa (EPS) is a rare reactive perforating dermatosis that is characterized by the transepidermal elimination of abnormal elastic fibers. Penicillamine, which is one of the clear triggers for EPS, is a heavy metal chelator that is primarily used for disorders such as cystinuria and Wilson¡¯s disease. It may cause alterations in the dermal elastic tissue such as pseudo-pseudoxanthoma elasticum, acquired cutis laxa, EPS and anetoderma. Herein we present a case of cutis laxa and EPS in a 34-year-old man who was previously on a long-term, high-dose of penicillamine for Wilson¡¯s disease. The combination of EPS and cutis laxa induced by penicillamine has rarely been reported and we report the first such case in Korea.
|
|
KEYWORD
|
|
Cutis laxa, Elastosis perforans serpiginosa, Penicillamine, Wilson¡¯s disease
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|